Autacoids are enzymatically derived chemical mediators with distinct biological activities and molecular structures.
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The activating stimulus may include bacterial lipopolysaccharides, muramyl dipeptide, and other chemical mediators.
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When mast cells degranulate, the release of chemical mediators ( histamine, cytokines ) leads to allergic symptoms and possibly anaphylaxis.
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His research contributions included work on correlating skin diseases with calcium metabolism and parathyroid hormone, and vascular chemical mediators involved in cutaneous inflammation.
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Typically, in other forms of shock, the sympathetic nervous system triggers various compensatory mechanisms by releasing epinephrine and norepinephrine, its major chemical mediators.
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Szczeklik's main research interest included : cardiopulmonary diseases, aspirin-induced asthma, chemical mediators in diseases of circulatory and respiratory systems with special reference to eicosanoids.
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Macrophages are responsible for the production of various cytokines, RNS and ROS, growth factors and chemokines as a response to activation signal such as chemical mediators, cytokines and lipopolysaccharide.
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The mechanism that is thought to have a significant influence on delayed effects involves formed blood cells and chemical mediators, which cause brain lipid peroxidation ( degradation of unsaturated fatty acids ).
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In periodontitis, however, the chemical mediators, or by-products, of chronic inflammation stimulate the osteoclasts, causing them to work more rapidly than the cells that build bone.
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Activated mast cells and basophils undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators ( cytokines, interleukins, leukotrienes, and prostaglandins ) from their smooth-muscle contraction.